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Argireline INCI Name: Acetyl Hexapeptide-8
Argireline is a trade name. The INCI name is Acetyl Hexapeptide-8. What to declare on the label, and how to check the quotation names the same substance.
Argireline is one of the most widely quoted cosmetic peptides and one of the most commonly mis-declared, because the trade name is so established that it starts to feel like the ingredient name.
The name pair
| Trade name | INCI name | Also seen as |
|---|---|---|
| Argireline, Acetyl Hexapeptide-3 (older usage) | Acetyl Hexapeptide-8 | Acetyl Hexapeptide-3 appears in older literature and older trade material. |
The current inventory entry is Acetyl Hexapeptide-8. If a document you are relying on uses “Acetyl Hexapeptide-3”, that is a legacy name — check it against the current inventory before it goes on a label.
How it appears on a label
Aqua, Glycerin, Acetyl Hexapeptide-8, Sodium Hyaluronate, Phenoxyethanol
Not “Argireline”. Not “hexapeptide”. Not “Acetyl Hexapeptide-3” on a new product.
What to check on the quotation
Because the trade name carries so much recognition, a quotation that says only “Argireline” leaves the actual material undefined. Ask for:
- The INCI name in writing, spelled as the inventory spells it
- Whether the material is supplied as a solution or a powder, and at what concentration
- Lot-specific COA with HPLC purity and MS identity
- Whether the product is synthetic or fermentation-derived, if that matters to your claims
The solution-versus-powder point matters more than buyers expect: a 1% solution and a pure powder need entirely different use-level arithmetic, and a quotation that does not say which one it is can be out by a factor of a hundred.
Claims discipline
Argireline is often marketed with language borrowed from injectable treatments. That language is not available to a cosmetic product, and repeating it in product copy is a compliance risk rather than a marketing advantage. Describe the role of the ingredient in the formulation, not a clinical outcome.
Frequently asked questions
What is the INCI name of Argireline?
Acetyl Hexapeptide-8. Older documents sometimes use Acetyl Hexapeptide-3, which is a legacy name — check against the current inventory before using it on a label.
Is Argireline the same as Acetyl Hexapeptide-3?
They refer to the same peptide in older literature, but the current declarable name is Acetyl Hexapeptide-8.
Is it supplied as a powder or a solution?
Both are common. The quotation must say which, and at what concentration, because the use-level arithmetic differs completely.
Can I put 'Argireline' on the ingredient list?
No. Trade names are not declarable ingredient names. Use the INCI name.
What documentation should come with the lot?
A lot-specific COA showing HPLC purity and MS identity confirmation, plus the INCI name and the form of supply in writing.