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Matrixyl 3000 INCI Name: Two Entries, Not One

Matrixyl 3000 is a trade name for a blend. On a label it becomes two separate INCI entries — and how you list them depends on how the blend was supplied.

Matrixyl 3000 is the trade name most often quoted for a peptide blend used in anti-ageing serums. Unlike a single peptide, it does not map to one INCI entry, and that is where labelling goes wrong.

What is actually in it

Trade nameINCI entriesNote
Matrixyl 3000 Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
A blend of two palmitoylated peptides. Both are declared separately.
Matrixyl (original, often called Matrixyl 3000 by mistake) Palmitoyl Pentapeptide-4 Different substance. Not interchangeable on a label.

How it appears on a label

Because Matrixyl 3000 is a blend, the ingredient list carries both entries, each in its own position according to concentration:

Aqua, Glycerin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Cetearyl Alcohol, Phenoxyethanol

There is no combined entry called “Matrixyl 3000” and no single INCI name that covers the blend. If a supplier tells you the INCI name is Matrixyl 3000, the answer is incomplete.

Three practical consequences

1. Order by the two names, not by the trade name. Ask the supplier to state both INCI names, the ratio of the two peptides, and whether the material is supplied as a blend or as the two components separately. The answer changes how you declare it.

2. Check for the common substitution. Palmitoyl Pentapeptide-4 is a different peptide that is sometimes offered as “Matrixyl”. It is a legitimate ingredient, but declaring it as Matrixyl 3000 is wrong.

3. Confirm the carrier. Many commercial Matrixyl grades are supplied in a carrier such as glycerin or a glycol. That carrier is part of what you bought and it belongs in your formulation arithmetic, not just on the label.

Specification points worth putting in writing

Frequently asked questions

What is the INCI name for Matrixyl 3000?

It is a blend, so there are two: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. Both are listed separately on the ingredient list.

Is Matrixyl the same as Matrixyl 3000?

No. Matrixyl is Palmitoyl Pentapeptide-4. Matrixyl 3000 is the two-peptide blend above. They are different substances with different INCI entries.

Do I list the carrier on the label?

If the carrier is a declarable ingredient, yes. It is part of what you purchased and part of the finished formula, so account for it in both the label and your formulation.

Can I declare it as a single ingredient if my supplier pre-blended it?

The blend still resolves to two INCI entries. Pre-blending does not create a new ingredient name.

What should the COA show?

Identity for both peptides, the peptide content of the supplied material, the carrier, and the lot number matching what was shipped.

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